Cushman & Wakefield has moved its Lower Manhattan headquarters to One World Trade Center. The firm now occupies 10,122 square feet of build-to-suit space on the 45th floor of the Western Hemisphere’s tallest building. It had previously occupied an office at 100 Wall Street.

“One of the world’s great real estate companies is now located in one of the world’s great buildings,” said Ron Lo Russo, president of Cushman & Wakefield’s New York Tri-State Region. “One World Trade Center stands at the center of the action Downtown. We are thrilled to call it our new home.”

“This world-renowned address is the perfect complement to our world-renowned brand,” said Cushman & Wakefield Executive Vice Chairman Tara Stacom. “The space is also ideal for us because its column-free design allows for a more open and collaborative work environment.”

“Like every tenant here, we also benefit from the One World Trade Center address itself,” said Ms. Stacom. “The address brings an added measure of marketing value, because the building’s name is universally known and respected.”

Cushman & Wakefield represents The Durst Organization in leasing One World Trade Center. On the ownership side, the team that closed this transaction included Ms. Stacom as well as Alan Stein, James Searl, and Justin Royce, along with Jodi Pulice of JRT Realty. Cushman & Wakefield represented itself on the tenant side.

Global publishing giant Condé Nast, the anchor tenant, situated its 1.2-million-square-foot headquarters between the 20th and 44th floors.

In addition to Condé Nast, the following firms have taken space and are operational in the building: Legends Hospitality, LLC; Incandescent Technologies, which provides information management consulting services to financial institutions; independent asset manager C12 Capital Management; global executive office space provider Servcorp; telecommunications consulting firm Symphony Communications; WTC retail developer Westfield America, global digital gaming company High 5 Games, and The Durst Organization’s downtown office.

Other tenants include: China Center New York LLC, a division of Vantone Industrial Co., Ltd; investment advisor Casablanca Capital; digital media company Tinypass, Inc.; Olam Americas, a division of Olam International a leading agri-business firm; xAd, a technology advertising firm; among several others.